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The inter-relationship hematological parameters between Saudi newborns and parents
Zainab A Babay1, Mohammed H Addar, Arjumand S Warsy
1Department of Obstetrics & Gynecology, College of Medicine, King Khalid University Hospital, Riyadh 11472, Kingdom of Saudi Arabia. maddar2001@hotmail.com
Saudi Medical Journal
|September 18, 2002
Summary
Genetic factors influence newborn hematological parameters. Red blood count, mean corpuscular volume, mean corpuscular hemoglobin concentration, and packed cell volume show significant correlation between Saudi parents and newborns, suggesting heritability.
Area of Science:
- Hematology
- Genetics
- Neonatal Medicine
Background:
- Understanding the heritability of hematological parameters in newborns is crucial for identifying genetic predispositions and distinguishing them from environmental influences.
- Previous research has explored familial correlations in various populations, but specific data for Saudi neonates and their parents is limited.
Purpose of the Study:
- To investigate the relationship between hematological indices in Saudi newborns and their parents.
- To determine which hematological parameters may be genetically influenced.
Main Methods:
- A cross-sectional study was conducted at King Khalid University Hospital, Riyadh.
- Blood samples were collected from 82 healthy Saudi pregnant women, their husbands, and their newborns' umbilical cords.
- Hematological indices and transferrin levels were analyzed.
Main Results:
- Significant correlations were observed between parents and cord blood for red blood count, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and packed cell volume.
- No significant correlation was found for hemoglobin and transferrin levels between parents and newborns.
Conclusions:
- Certain hematological parameters, including red blood count, mean corpuscular volume, mean corpuscular hemoglobin concentration, and packed cell volume, appear to be genetically determined in Saudi newborns.
- Hemoglobin and transferrin levels are likely more influenced by environmental factors, as evidenced by the lack of correlation between parents and newborns.