Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endocarditis caused by Abiotrophia defectiva in children.

Hsiu-Hao Chang1, Chun-Yi Lu, Po-Ren Hsueh

  • 1Department of Pediatrics, National Taiwan University Hospital, Taipei.

The Pediatric Infectious Disease Journal
|September 19, 2002
PubMed
Summary

Abiotrophia defectiva, a common oral bacterium, can cause infective endocarditis, particularly in children. This case highlights successful antibiotic treatment for a pediatric mitral valve infection caused by this organism.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recommendations and guidance for pneumococcal vaccination for adults in Taiwan.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2026
Same author

Letermovir for cytomegalovirus prophylaxis in pediatric allogeneic hematopoietic stem cell transplantation: a single-center experience.

Blood research·2026
Same author

Low flow cytometry events in detecting CNS involvement in pediatric B-cell precursor ALL: NGS validation and prognostic significance.

Blood advances·2026
Same author

O-GlcNAcylation expression predicts a favorable prognosis and mitigates malignant phenotypes via MYCN suppression in neuroblastoma.

Molecular and cellular pediatrics·2026
Same author

Genetic landscape of pediatric acute myeloid leukemia in Taiwan.

Scientific reports·2026
Same author

Preemptive NUDT15 Genotyping and Its Impact on Febrile Neutropenia in Pediatric Patients With Acute Lymphoblastic Leukemia in Taiwan.

Journal of pediatric hematology/oncology·2025

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Cardiology

Background:

  • Abiotrophia defectiva, previously known as nutritionally variant streptococci, is a component of normal oral flora.
  • These bacteria are increasingly recognized as a potential cause of infective endocarditis, especially culture-negative cases.

Observation:

  • A case of infective endocarditis caused by Abiotrophia defectiva involving the mitral valve in a 12-year-old girl is presented.
  • The patient underwent a standard 8-week course of antibiotic therapy.

Findings:

  • The pediatric patient achieved a symptom-free status 6 months post-discharge, indicating successful treatment.
  • A review of pediatric cases of nutritionally variant streptococcal endocarditis since 1971 was conducted.

Related Experiment Videos

Implications:

  • This case underscores the importance of considering Abiotrophia defectiva in the differential diagnosis of pediatric infective endocarditis.
  • Effective antibiotic management can lead to favorable outcomes in children with Abiotrophia defectiva endocarditis.