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The Self-association of Melittin at Low Concentration in Aqueous Solution
1National laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China.
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao Acta Biochimica Et Biophysica Sinica
|January 1, 1996
Abstract:
The intrinsic fluorescence emission, polarization and Trp-19 quenching of melittin in the aqueous solution showed that even with concentration as low as 2 &mgr;M, the self-association of melittin still occurred. The transition preferred to occur under acidic condition and the stability of the associated melittin was dependent on the pH value of the solution.