The Distributive Study of Plasmalogen in Guinea Pig Tissues

The content of plasmalogen and plasmenylethanolamine (PE-plasmalogen) in the guinea pig brain, heart, liver, lung, kidney and muscle were examined and compare to the total phospholipids and total phosphatidylethanolamine (PE) of these organs, by the methods of Gottfried iodine and thin layer chromatography. The highest content of plasmalogen and PE-plasmalogen was found in the brain, which was 9.28 and 6.54 &mgr;mol/g of tissue respectively, followed was in the heart which was 5.29 and 2.01 &mgr;mol/g of tissue respectively. The lowest content of plasmalogen and PE-plasmalogen was in the liver, which was 1.47 and 0.67 &mgr;mol/g of tissue respectively. It was also found that the content of PE-plasmalogen in the muscle of the guinea pig was higher than that in the kidney, lung and liver, it accounts for 40.1% of the total PE. The distributing regularity and biological significance of plasmalogen in guinea pig tissues were discussed.