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Summary
Zenker's diverticulum, a rare condition, can develop cancer. This case highlights a 55-year-old woman successfully treated for epidermoid carcinoma within a pharyngoesophageal outpouching.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Zenker's diverticulum is a pharyngoesophageal outpouching, typically diagnosed in elderly patients.
- Malignancy within a Zenker's diverticulum is exceptionally rare, with fewer than 23 reported cases.
Observation:
- A 55-year-old female presented with dysphagia and regurgitation of bloodstained material.
- Diagnostic imaging (barium swallow) and esophagoscopy revealed a neoplastic mass.
- Biopsy confirmed the presence of epidermoid carcinoma.
Findings:
- The patient underwent wide field resection of the diverticulum and carcinoma.
- Post-operative treatment included irradiation and pharyngoesophageal reconstruction.
- The patient achieved a disease-free status at three-year follow-up.
Implications:
- This case underscores the importance of investigating persistent symptoms in patients with Zenker's diverticulum.
- Early diagnosis and multimodal treatment (surgery, irradiation) can lead to favorable outcomes for rare pharyngoesophageal cancers.
- Highlights the need for vigilance in diagnosing malignancy in uncommon locations.