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Updated: Sep 10, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 17, 2014
[A post-mortem analysis of 712 cases of congenital heart disease (author's transl)]
Insights
Congenital cardiovascular malformations occurred in 32.1% of pediatric autopsies. Transposition of the great arteries, tetralogy of Fallot, and ventricular septal defects were the most common congenital heart diseases.
Area of Science:
- Pediatric Pathology
- Cardiovascular Medicine
- Medical Genetics
Context:
- Autopsy data from children under 16 years old.
- Study conducted at the Department of Pathology, Institute of Pediatrics in Warsaw.
- Retrospective analysis spanning from 1959.
Purpose:
- To analyze the incidence and patterns of congenital cardiovascular malformations in a pediatric autopsy cohort.
- To present the frequency of specific congenital heart diseases using a novel classification system.
- To examine age distribution, causes of death, and co-occurrence with other congenital anomalies.
Summary:
- Congenital cardiovascular malformations were identified in 712 (32.1%) of 2159 pediatric autopsies.
- The most frequent malformations included transposition of the great arteries, tetralogy of Fallot, and ventricular septal defects.
- Analysis included age distribution, causes of death, and association with other congenital malformations.
Impact:
- Provides epidemiological data on congenital heart diseases in a pediatric population.
- Highlights the prevalence of specific malformations, aiding in diagnostic and research focus.
- Informs understanding of the spectrum and associated conditions of congenital cardiovascular malformations.
Abstract:
Congenital cardiovascular malformations were found in 712 cases (32.1%) out of 2159 autopsies, performed on children less than 16 years old, at the Department of Pathology of the Institute of Pediatrics in Warsaw since 1959. A detailed retrospective analysis of all the cases was performed. The author's own classification of congenital heart diseases was used in this analysis. The incidence of particular heart malformations or syndromes was presented. The most frequent ones were: transposition of the great arteries, tetralogy of Fallot and ventricular septal defects, in a decreasing frequency. An analysis of the age distribution of various cardiac malformations and a short analysis of the causes of death was made. The incidence of congenital heart diseases accompanied by other congenital malformations was analysed.
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