[Changes in cerebral metabolism during experimental anuria]

After experimental ureterotomy in mice, the changes which occurred in cerebral metabolism were studied. A significant increase in the cerebral glucose and glycogen level as well as of degradation power was noticed 25 hours after the operation. The level of lactic acid production in the same period of renal insufficience indicated a gradual decreasing tendency. These results as well as further details are discussed with regard to the underlying disturbances.