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Synthesis and DNA-binding properties of dinuclear platinum(II)-amine complexes of 1,7-dicarba-closo-dodecaborane(12)
1Department of Chemistry, University of Adelaide, Adelaide 5005, Australia.
Chemical Communications (Cambridge, England)
|September 21, 2002
Abstract:
The first examples of platinum(II)-amine complexes containing a dicarba-closo-dodecaborane(12) (carborane) moiety are described; preliminary in vitro DNA-binding experiments indicate that the complexes are capable of targetting plasmid DNA.