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Updated: Aug 14, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
Published on: April 3, 2014
Incorporation of a novel nucleobase allows stable oligonucleotide-directed triple helix formation at the target
D Guianvarc'h1, R Benhida, J L Fourrey
1Institut de Chimie des Substances Naturelles, CNRS, Avenue de la Terrasse 91198. Gif-sur-Yvette, France.
Abstract:
Thermal denaturation experiments have established that an oligonucleotide incorporating the artificial nucleobase S, does form a stable triplex with a double stranded DNA which exhibits a pyrimidine interruption within the oligopurine sequence.
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