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Further halotyrosine derivatives from the marine sponge Suberea aff. praetensa
Anake Kijjoa1, Rawiwan Watanadilok, Pichai Sonchaeng
1Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Portugal.
Zeitschrift Fur Naturforschung. C, Journal of Biosciences
|September 21, 2002
Abstract:
Reexamination of the marine sponge Suberea aff. praetensa, (Row) from the Gulf of Thailand furnished in addition to bromotyrosine derivatives found previously 5-bromo- and 5-chlorocavernicolin, cavernicolins 1 and 2, two other brominated tyrosine metabolites, a known bisoxazolidone and a new unusual rearranged tyrosine metabolite subereatensin. Several of the metabolites exhibited significant inhibitory effects against five human cancer cell lines.