Related Experiment Video
Updated: Sep 29, 2026

Design and Synthesis of a Reconfigurable DNA Accordion Rack
Published on: August 15, 2018
Scaling in DNA unzipping models: denaturated loops and end segments as branches of a block copolymer network
Marco Baiesi1, Enrico Carlon, Attilio L Stella
1INFM, Dipartimento di Fisica, Università di Padova, I-35131 Padova, Italy.
Abstract:
For a model of DNA denaturation, exponents describing the distributions of denaturated loops and unzipped end segments are determined by exact enumeration and by Monte Carlo simulations in two and three dimensions. The loop distributions are consistent with first-order thermal denaturation in both cases. Results for end segments show a coexistence of two distinct power laws in the relative distributions, which is not foreseen by a recent approach in which DNA is treated as a homogeneous network of linear polymer segments. This unexpected feature, and the discrepancies with such an approach, are explained in terms of a refined scaling picture in which a precise distinction is made between network branches representing single-stranded and effective double-stranded segments.
Related Concept Videos
Radical Chain-Growth Polymerization: Chain Branching
Ziegler–Natta Chain-Growth Polymerization: Overview
The Replisome
The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with the...
Step-Growth Polymerization: Overview
Many natural and synthetic polymers are produced by...
Radical Chain-Growth Polymerization: Overview
Characteristics and Nomenclature of Copolymers

