Success of serial external electrical cardioversion of persistent atrial fibrillation in maintaining sinus rhythm; a

E Bertaglia1, D D'Este, F Zerbo

  • 1Dipartimento di Cardiologia, Ospedale Civile, Mirano, Venice, Italy.

European Heart Journal
|September 21, 2002
PubMed

Insights

An aggressive strategy of repeated electrical cardioversion effectively maintained sinus rhythm in patients with persistent atrial fibrillation for 12 months. This approach also improved left ventricular ejection fraction compared to standard care.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Persistent atrial fibrillation (AF) poses a significant clinical challenge.
  • Maintaining sinus rhythm is crucial for improving patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy of a serial external electrical cardioversion strategy.
  • To assess its success in maintaining sinus rhythm over 12 months in recurrent persistent AF patients.

Main Methods:

  • Prospective, randomized study of 90 patients with persistent AF.
  • Group AGG: repeated electrical cardioversion for AF relapse within 1 month.
  • Group CTL: no treatment for AF relapse; all patients received antiarrhythmic drugs.

Main Results:

  • Sinus rhythm maintained at 12 months: 53% in Group AGG vs. 29% in Group CTL (P<0.03).
  • Significant recovery of left ventricular ejection fraction in Group AGG at 6 months (P<0.001).

Conclusions:

  • An aggressive policy of repeated electrical cardioversion is effective for maintaining sinus rhythm.
  • This strategy is beneficial for patients experiencing early AF recurrence.
Abstract

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...