Identification of 1088 new transposon insertions of Caenorhabditis elegans: a pilot study toward large-scale screens

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Quantitative and Automated High-throughput Genome-wide RNAi Screens in C. elegans
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Quantitative and Automated High-throughput Genome-wide RNAi Screens in C. elegans

Published on: February 27, 2012

Edwige Martin1, Hélène Laloux, Gaëlle Couette

  • 1CGMC, CNRS-UMR 5534, Université Lyon1, 69100 Villeurbanne, France.

Genetics
|September 21, 2002
PubMed

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Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...