Nonepithelial tumor-like lesions of the prostate: a never-ending diagnostic problem

Nonepithelial tumor-like lesions of the prostate include benign prostatic hyperplasia-associated stromal nodules, postoperative spindle cell nodules, benign mesenchymal tumors and sarcomas. These lesions and neoplasms are rare but need to be exactly classified for adequate treatment. This review focuses on the differential diagnosis between the various benign and malignant entities and compares the new WHO classification with a recently published typing of prostatic stromal lesions of unknown malignant potential.