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Bovine fetal cerebral absidiomycosis

W U Knudtson, M E Bergeland, C A Kirkbride

    Sabouraudia
    |November 1, 1975
    PubMed

    Insights

    A rare case of fetal cerebral mycosis in cattle was identified, caused by Absidia corymbifera. Despite the infection, fetal antibodies against the fungus were not detected, suggesting a complex immune response.

    Area of Science:

    • Veterinary Pathology
    • Mycology
    • Immunology

    Background:

    • Fungal infections in bovine fetuses are uncommon.
    • Absidia corymbifera is a known opportunistic pathogen.

    Observation:

    • One case of fetal cerebral mycosis was diagnosed in 4015 aborted bovine fetuses.
    • The infection was associated with severe brain lesions including vasculitis, thrombosis, abscessation, and cavitation.

    Findings:

    • Absidia corymbifera was identified as the causative agent.
    • No antibodies against A. corymbifera or other fungal antigens were detected in fetal serum using immunodiffusion.
    • Elevated levels of Immunoglobulin G (IgG) were found in the fetal serum via radial-immunodiffusion assay.

    Implications:

    • This case highlights the potential for Absidia corymbifera to cause severe fetal disease in cattle.
    • The absence of detectable antibodies despite infection suggests potential immune evasion strategies by the fungus or limitations in fetal immune response.
    • Further research is needed to understand the pathogenesis and immune response to fetal cerebral mycosis in cattle.

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