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Antibiotic resistance and the need for the rational use of antibiotics
1Department of Family Medicine, Medical University of South Carolina, Charleston 29524, USA. huestowj@musc.edu
Abstract:
Antibiotic resistance has increased dramatically over the past 10 years. In many countries, penicillin resistance to Streptococcus pneumoniae is nearly 50% with resistance to other drugs rising as well. One of the mechanisms responsible for the development of resistance is the widespread use of antibiotics in the primary care setting, chiefly for the treatment of respiratory disorders. Reduction in antibiotic prescribing for respiratory diseases in primary care has been associated with decreases in drug resistance in Streptococcus pneumoniae. This article will review common reasons for overuse of antibiotics in primary care settings and some strategies for reducing injudicious antibiotic prescribing.
Insights
Antibiotic resistance in Streptococcus pneumoniae is rising due to widespread antibiotic use for respiratory infections. Reducing primary care antibiotic prescribing can decrease this drug resistance.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Antibiotic resistance, particularly penicillin resistance in Streptococcus pneumoniae, has risen significantly.
- Widespread antibiotic use in primary care for respiratory conditions is a key driver of resistance.
- Decreased antibiotic prescribing in primary care correlates with reduced Streptococcus pneumoniae resistance.
Purpose of the Study:
- To review common reasons for antibiotic overuse in primary care.
- To identify strategies for reducing injudicious antibiotic prescribing.
Main Methods:
- Literature review of antibiotic prescribing patterns in primary care.
- Analysis of the relationship between prescribing rates and antibiotic resistance data.
Main Results:
- Overuse of antibiotics in primary care is prevalent for respiratory disorders.
- Reduced prescribing has demonstrated a positive impact on decreasing resistance.
Conclusions:
- Strategies to curb unnecessary antibiotic prescriptions are crucial for combating resistance.
- Interventions targeting primary care prescribing practices can mitigate the rise of antibiotic resistance.
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