Related Experiment Video
Updated: Sep 29, 2026
Accessing Early Differentiation of Virus-Specific Follicular Helper CD4+ T Cell in Acute LCMV-Infected Mice
Published on: April 26, 2024
Follicular mucinosis associated with early stage cutaneous T-cell lymphoma: successful treatment with interferon
G J Kontochristopoulos1, D Exadaktylou, E Hatziolou
12nd Department of Dermatology, A Syngros Hospital, Athens, Greece.
Background:
Follicular mucinosis (FM) is a rare dermatosis characterized by mucin deposits in the pilosebaceous units. It is divided into a primary-benign type and a secondary type associated mostly with lymphomas. No standard effective therapy is available for the primary FM while in the secondary form treatment is aimed against the underlying disease.
Methods:
We report a case of secondary FM in which a cutaneous T-cell lymphoma was detected 6 years after the initial eruption.
Results:
Complete remission was achieved with combination therapy of interferon alpha-2b at a dose of 6 million U subcutaneously three times a week, and acitretin 35 mg/day, for 6 months.
Conclusion:
Regular clinical and histopathological evaluation is suggested for all patients with FM. For cases associated with cutaneous T-cell lymphoma the combination of interferon alpha and acitretin seems to be a good therapeutical approach.
