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Updated: Aug 11, 2026

Murine Colitis Modeling using Dextran Sulfate Sodium (DSS)
Published on: January 19, 2010
Pattern of aganglionic megacolon in Calabar, Nigeria
1Paediatric Surgery Unit, Department of Surgery, University of Calabar, Nigeria.
Hirschsprung
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Congenital Disorders
Background:
- Hirschsprung's disease is a congenital condition causing intestinal obstruction.
- Late diagnosis in the study area was linked to poverty and lack of awareness.
- Common symptoms included abdominal distension, constipation, and growth retardation.
Purpose of the Study:
- To report on cases of Hirschsprung's disease at UCTH.
- To highlight challenges in diagnosis and treatment.
- To advocate for public awareness campaigns.
Main Methods:
- Retrospective review of 21 pediatric cases.
- Analysis of patient presentation, symptoms, and treatment outcomes.
- Surgical management including resection and colostomy.
Main Results:
- 21 children diagnosed with Hirschsprung's disease between 1996-1998.
- Late presentation was a significant issue.
- Surgical resection with colostomy was the standard treatment.
Conclusions:
- Surgical intervention improves outcomes for Hirschsprung's disease.
- Public awareness is crucial for early diagnosis and prevention of complications.
- Addressing socioeconomic factors is key to improving patient outcomes.
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