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[The meningoencephalitis syndrome in brain tumor]
Psychiatrie, Neurologie Und Medizinische Psychologie. Beihefte
|January 1, 1977
Summary
Cerebrospinal fluid pleocytosis in brain tumor patients was more common in malignant and fluid canal system tumors. However, cell counts alone did not predict tumor type or location.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Cerebrospinal fluid (CSF) analysis is crucial for diagnosing neurological conditions.
- Pleocytosis, an elevated cell count in CSF, can indicate various pathologies, including brain tumors.
- Understanding the relationship between pleocytosis and tumor characteristics aids in diagnosis and management.
Observation:
- A retrospective study evaluated 765 patients with brain tumors treated since 1951.
- CSF records were analyzed for pleocytosis (defined as >15/3 cells).
- 181 patients (24%) exhibited significant pleocytosis.
Findings:
- No definitive correlation was found between the degree of pleocytosis and tumor biological valence or localization.
- Pleocytosis occurred more frequently in malignant brain tumors.
- Tumors associated with the fluid canal system (e.g., plexus papillomata, ependymomata, craniopharyngeomata) showed a higher incidence of pleocytosis.
Implications:
- While pleocytosis is more frequent in certain brain tumor types, it is not a specific diagnostic marker for tumor type or location.
- The findings contribute to understanding unspecific meningeal irritative syndromes in the context of brain tumors.
- Further research may refine the diagnostic utility of CSF analysis in neuro-oncology.