[Onset of the disease process in endemic nephropathy]

Patients with endemic nephropathy family aggravation are described, that had left-their native endemic villages at the age of 6 months to 6 years and had lived in non-endemic settlements and in spite of that suffered and died of endemic nephropathy. The diagnosis, of all of themt is pathologoanatomically and histomorphologically confirmed. It is concluded that a long time sojourn in the endemic region is not necessary for those born there with endemic nephropathy family aggravation, in order to suffer of the same disease even in the new residence. The author admits, based on those data, that the beginning of the pathological process of endemic nephropathy is during the first infant years, so that the children of sick patients would be the best objects for investigation of the endemic nephropathy initial stage.