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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Dermatoglyphics in Noonan's syndrome (author's transl)]
Acta Geneticae Medicae Et Gemellologiae
|January 1, 1975
Summary
Dermatoglyphic analysis in Noonan syndrome revealed no general population deviations, except for increased fingertip whorls and specific axial triradius t positions in some patients. These findings offer insights into genetic markers for Noonan syndrome.
Area of Science:
- Genetics
- Dermatoglyphics
- Human Biology
Context:
- Noonan syndrome is a genetic disorder with variable expressivity.
- Dermatoglyphics, the study of skin patterns, can provide insights into genetic conditions.
- Previous dermatoglyphic studies have explored various genetic syndromes.
Purpose:
- To investigate dermatoglyphic patterns in individuals with Noonan syndrome.
- To compare these patterns with those of the general population and related syndromes.
Summary:
- A dermatoglyphic analysis was conducted on 12 individuals (7 boys, 5 girls) with Noonan syndrome.
- No significant deviations from general population values were observed for most quantitative dermatoglyphic traits.
- An increased frequency of fingertip whorls and specific axial triradius t positions (t' or t") was noted, similar to findings in Turner syndrome.
Impact:
- Identifies specific dermatoglyphic markers that may be associated with Noonan syndrome.
- Contributes to understanding the phenotypic variability and genetic underpinnings of Noonan syndrome.
- May aid in the diagnosis or genetic counseling for Noonan syndrome through dermatoglyphic examination.
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