Haptoglobin type Hp-Jo and hypohaptoglobinaemia in a Danish family. Preliminary report

The occurrence of the rare Hp 2-Jo type in a Danish family is reported. By subtyping procedure the 2alphaJ polypeptide chain was demonstrated for the first time in an HP 2-Jo sample. Apparently independent of the transmission of the HpJo gene hypohaptoglobinaemia was found in a rather high proportion of the members of the kindred.