[Excretion of testosterone in men with various forms of hypogonadism]

A reduction of testosterone excretion in men with hypogonadism is reported in literature; however, the clinical peculiarity of its individual forms are not considered in these works. This paper treats of testosterone excretion in 43 patients with various forms of hypogonadism, of this number in 36 before and after a single testosterone-propionate loading. There was seen a reduction of testosterone excretion in hypogonadism. Secondary hypogonadism coursed against the background of a more marked insufficiency of testosterone excretion than the primary one. In a number of hypogonadism cases testosterone excretion remained unchanged and their clinical signs were caused by an inadequate realization of the androgenic effect. In hypogonadism an increase of the urinary excretion following its administration did not always correspond to the dose of the administered hormone, which could serve as one of the pathogenetic mechanisms of development of the disease.