[Autoregulation of the somatic function of the adenohypophysis in intact and thyroidectomized rats]

Experiments conducted on male rats showed exogenous STH (2 mg daily for 10 days, subcutaneously) to cause a reduction in the STH content in the adenohypophysis and in the incorporation of labeled amino acids into the SHT in vitro both in intact and in thyroidectomized animals. Exogenous STH somewhat normalized the increase in body weight and the weight of the adenohypophysis of the thyroidectomized animals. A conclusion was drawn that autoregulation of the somatotropic function of the adenohypophysis persisted under conditions of a marked thyroid hormone deficiency.