[Characteristics of anaphylactic reactions to antibiotics administered under anesthesia]

Wide application of active chemical and biological substances in medical practice is inevitably associated with the appearance of adverse side reactions sometimes hazardous for patients' life. Especially grave allergic reactions are observed to antibiotics administered under narcosis. Narcosis would inhibit an anaphylactic response, but with its cessation when the allergen concentration in blood is high enough an extremely rapid anaphylactic reaction would develop that promptly resulted in a terminal patients' condition. Three case reports are described. Reanimation measures proved to be a success only in 2 cases.