[Dynamic tracing of effective renal plasma flow with 131-I-hippuran]

Results are reported from the carried out dynamic follow-up of the effective renal plasma flow (ERP), determined by 131I-hippuran in 55 patients according to the method of single injection. An improvement of the ERP values was established in 56,4 per cent, while the simulataneously performed isotope nephrography (ING) gave considerably lower percentage. That fact emphasizes the advantage of 131I-hippuran clearance, not only for the diagnosis of disturbed renal function but in the dynamic follow-up of the developed improvement as well. In patients with deteriorated ERP values, the carried out ING showed deterioration in only 42.9 per cent. The carried out parallel investigations for establishing the dynamic changes in the renal function reveal the higher sensitivity of 131I-hippuran clearance as compared with ING.