[A clinical report of norethisterone-3-oxime-acetate vacation pill]

This paper reported the clinical application of Norethisterone-Oxime-Acetate used as a "vacation" pill. The result indicated that pregnancy could be prevented in women who received this drug orally when they themselves or their husband came home on leave. A dose of 2 mg was administered for women on the 1st day when the couples live together, then followed by 1 mg daily successively and an additional pill was given on the morning next to the end of the leave. A high efficacy of 99.75% in terms of cycles proved in 604 women with 825 treated cycles of 604 women. The changes in menstrual cycles, the duration of menstrual bleeding and the amount of flow after treatment were very slight. The incidence of the intermenstrual bleeding and withdrawal bleeding were 2.16%. The author's observation showed that Norethisterone-oxime-Acetate is an active contraceptive pill and possesses the advantages of not only high efficacy, low side effect, but also convenience in use.