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[Danazol: a new hormonal post-coital contraceptive method]
Abstract:
During a 9-month period, 84 female patients received post-coital contraception consisting either of an association of ethinyl estradiol/norgestrel or of danazol, in order to compare the safety and any adverse reaction of these 2 treatments. Overall, the patients treated with danazol presented 1/3 as many side effects. Nausea was reduced to 1/3 in frequency and vomiting to 1/9 in this group. 5 pregnancies were confirmed in the ethinyl estradiol/norgesterol group and 2 in the danazol group. Although more cases are needed, it would appear that danazol is characterized by greater efficacy and patient acceptability.
Keywords:
BiologyContraceptionContraceptive Agents, Estrogen--side effectsContraceptive Agents, Female--side effectsContraceptive Agents, Postcoital--side effectsContraceptive Agents, Progestin--side effectsContraceptive Agents--side effectsEndocrine SystemEthinyl Estradiol--side effectsFamily PlanningFertility Control, Postcoital--side effectsGastrointestinal EffectsHormones--side effectsNauseaNorgestrel--side effectsPhysiologySigns And SymptomsVomiting