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Related Experiment Videos

The progestagen releasing vaginal ring.

M Elstein, I D Nuttall

    Journal of Obstetrics and Gynaecology
    |January 1, 1985
    PubMed
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    The vaginal ring is a well-tolerated contraceptive delivery system for low-dose progestagens, showing low expulsion and satisfactory vaginal tolerance. This method offers high patient acceptability and convenience, potentially expanding progestagen-only contraception use.

    Area of Science:

    • Reproductive Health
    • Contraception
    • Vaginal Drug Delivery Systems

    Background:

    • Existing contraceptive methods can lead to patient disenchantment.
    • Vaginal contraception methods have shown potential for increased uptake.
    • Progestagen-only contraception is suitable for specific patient groups.

    Purpose of the Study:

    • To evaluate the efficacy and acceptability of a novel vaginal ring delivery system for low-dose progestagens.
    • To compare the performance of the vaginal ring with oral low-dose progestagens.
    • To assess patient satisfaction and suitability for various demographic groups.

    Main Methods:

    • Utilized data from the Manchester study and a multicenter study.
    • Assessed expulsion rates, vaginal tolerance, pregnancy rates, and bleeding patterns.
    Keywords:
    BiologyContraceptionContraception TerminationContraceptive Agents, FemaleContraceptive Agents, Progestin--administraction and dosageContraceptive Agents--administraction and dosageContraceptive Methods--historyContraceptive UsageDemographic FactorsEndocrine SystemEvaluationExaminations And DiagnosesFamily PlanningFertilityHormonesLevonorgestrel--administraction and dosageMethod AcceptabilityPhysical Examinations And DiagnosesPhysiologyPopulationPopulation DynamicsReproductive BehaviorVaginal Rings--history

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  • Included subjective patient assessments of the contraceptive method.

    • Main Results:

    • The vaginal ring demonstrated good tolerability and low expulsion rates.
    • Pregnancy and bleeding patterns were comparable to oral low-dose progestagens, with potential for improvement.
    • High patient enthusiasm and acceptability were reported, particularly among those dissatisfied with other methods.

    Conclusions:

    • The progestagen-only vaginal ring is a well-tolerated and highly acceptable contraceptive option.
    • Its convenience (reinsertion every 90 days) enhances use-effectiveness.
    • The method shows promise for wider application in progestagen-only contraception, especially for lactating, older, or family-spacing women.