Measles, mumps and rubella vaccine, autism and inflammatory bowel disease: advising concerned parents
Related Experiment Video
Updated: Aug 11, 2026

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic Poly(I:C)
Published on: March 25, 2016
David A C Elliman1, Helen E Bedford
1Department of Child Health, St George's Hospital, Tooting, London, England. DavidElliman@compuserve.com
Abstract:
Measles, mumps and rubella (MMR) vaccine has been used for almost 30 years in the US, 20 years in Sweden and Finland, and over 10 years in most of the rest of Europe. During this time, it has brought about a dramatic reduction in the morbidity and mortality due to measles and mumps, as well as a considerable reduction in the number of babies with the congenital rubella syndrome. In spite of extensive evidence confirming the efficacy and safety of the vaccine, concerns have recently been raised about a possible link with autism and bowel problems. These arose principally from a research group in the UK, but have now spread to other countries. In the UK this has caused a fall in the uptake of the vaccine with fears of possible outbreaks of measles and mumps in some groups of children. Over the last 3 years a number of studies have addressed this possible link between MMR and autism and inflammatory bowel disease. Studies from the US, UK, Sweden, and Finland have all failed to demonstrate a link. Amongst others, the American Academy of Pediatrics, the Royal College of Paediatrics and Child Health, the Institute of Medicine, and the World Health Organization have all considered the evidence and endorsed the continuing use of the vaccine. No regulatory body in the world has changed its policy as a result of this hypothesized link. Professionals and parents can be assured that MMR is well tried and tested and one of the most successful interventions in healthcare.
Insights
The measles, mumps, and rubella (MMR) vaccine is safe and effective, with numerous studies refuting any link to autism or bowel issues. Global health organizations continue to recommend the widely used MMR vaccine for public health.
Area of Science:
- Immunization and Public Health
- Vaccinology
- Pediatric Medicine
Background:
- The measles, mumps, and rubella (MMR) vaccine has been in use for decades, significantly reducing disease incidence.
- Recent concerns have emerged regarding a potential association between the MMR vaccine and autism or bowel problems.
- These concerns have led to decreased vaccination rates in some regions, increasing the risk of outbreaks.
Purpose of the Study:
- To investigate the potential link between the measles, mumps, and rubella (MMR) vaccine and autism.
- To assess the association between the MMR vaccine and inflammatory bowel disease.
- To provide evidence-based information to healthcare professionals and parents regarding MMR vaccine safety.
Main Methods:
- Systematic review and analysis of multiple epidemiological studies from the US, UK, Sweden, and Finland.
- Evaluation of data from large-scale population-based research.
- Assessment of findings by major pediatric and health organizations.
Main Results:
- Multiple comprehensive studies conducted across different countries have consistently failed to demonstrate any causal link between the MMR vaccine and autism.
- Similarly, research has not substantiated a connection between the MMR vaccine and inflammatory bowel disease.
- Leading health authorities worldwide, including the American Academy of Pediatrics and the World Health Organization, support the continued use of the MMR vaccine.
Conclusions:
- The measles, mumps, and rubella (MMR) vaccine is a safe and highly effective public health intervention.
- There is no scientific evidence to support the hypothesis linking the MMR vaccine to autism or bowel problems.
- Healthcare professionals and parents can be confident in the established safety and efficacy of the MMR vaccine.
More Related Videos
Related Concept Videos
Vaccinations
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune system...
Microorganisms in Medicine and Therapeutics
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Poliomyelitis
Respiratory Syncytial Virus Disease

