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Protein degradation with photoactivated enediyne-amino acid conjugates
Gary Plourde1, Ahmed El-Shafey, Farid S Fouad
1Department of Chemistry, Northeastern University, 360 Huntington Ave., Boston, MA 02115, USA.
Bioorganic & Medicinal Chemistry Letters
|September 25, 2002
Abstract:
A series of photoactivated enediynes was prepared, and successfully employed for the selective degradation of target proteins.