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Establishment of Epstein-Barr Virus Growth-transformed Lymphoblastoid Cell Lines
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Published on: November 8, 2011

Molecular mechanisms of B-lymphocyte transformation by Epstein-Barr virus

Gail A Bishop1, Lisa K Busch

  • 1Department of Microbiology, 3-570 Bowen Science Bldg., The University of Iowa, Iowa City, IA 52242, USA. gail-bishop@uiowa.edu

Microbes and Infection
|September 25, 2002
PubMed

The B-lymphotropic virus Epstein-Barr virus (EBV) has been implicated in the pathogenesis of B-cell malignancies, particularly in immunodeficient individuals. This review provides a brief overview of the EBV-encoded proteins involved in B-cell transformation, and the current state of knowledge about their roles in this process.

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