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Relation between maternal serum adenosine deaminase and plasma adenosine levels in twin pregnancies
Shunji Suzuki1, Yoshio Yoneyama, Rintaro Sawa
1Department of Obstetrics and Gynecology, Tokyo Rinkai Hospital, Tokyo 113-8603, Japan.
Objective:
The relationship between adenosine deaminase activity and plasma adenosine was examined in non-pregnancy as well as in singleton and twin pregnancies.
Methods:
Whole-blood samples were taken from 11 singleton and 11 dichorionic twin pregnant women during the third trimester. The plasma adenosine levels were assayed with a modified high-performance liquid chromatographic method, while the adenosine deaminase levels were measured enzymatically.
Results:
The adenosine deaminase and plasma adenosine levels were both higher in twin pregnancies compared to singleton and non-pregnancies.
Conclusion:
Increased plasma adenosine is not due to decreased serum adenosine deaminase levels in twin pregnant women.