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It takes "heart" to win: what makes the heart powerful?
Kerry S McDonald1, Todd J Herron
1Department of Physiology, University of Missouri, Columbia, Missouri 65212, USA.
Abstract:
The pumping action of the heart varies considerably on a beat-to-beat basis and is ultimately determined by the extent of ventricular myocyte shortening during systole. The use of isolated myocardial preparations has provided new insights about the subcellular factors that modulate power output of the ventricles.