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Updated: Sep 29, 2026

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
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Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation

Published on: March 4, 2016

Surgical Pearl: The "skin strip" method for harvesting tissue to graft chronic ulceration

Sarah L Woodrow1, Rohan K Mehta, Richard J Pye

  • 1Dermatology Department, Addenbrooke's Hospital, Cambridge, United Kingdom.

Journal of the American Academy of Dermatology
|September 25, 2002
PubMed
Abstract

No abstract available in PubMed .

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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