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Related Experiment Videos

Reentry in the atrium.

F I Bonke, M A Allessie, L N Bouman

    Bulletin Der Schweizerischen Akademie Der Medizinischen Wissenschaften
    |August 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Early premature beats can trigger reentry and tachycardia in atrial tissue, including working myocardium. This phenomenon, explained by the "leading circle" concept, highlights potential mechanisms for cardiac arrhythmias.

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    Area of Science:

    • Cardiology
    • Electrophysiology
    • Cardiac Anatomy

    Background:

    • Reentry is a critical mechanism underlying various cardiac arrhythmias.
    • Premature beats can initiate reentrant circuits in different cardiac tissues.

    Purpose of the Study:

    • To investigate the mechanisms of reentry and tachycardia initiation by premature beats in atrial tissue.
    • To explore the role of sinoatrial (SA) and atrioventricular (AV) nodes in reentrant phenomena.
    • To introduce and discuss the
    • leading circle
    • concept for circus movement tachycardia.

    Main Methods:

    • Studies using isolated rabbit atrial preparations.
    • Electrophysiological mapping of impulse spread during premature beats and tachycardia.

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  • Analysis of conduction block and retrograde activation patterns.

    • Main Results:

    • Premature beats can induce reentry in SA node (under ectopic drive), AV node, and working atrial myocardium.
    • Sinoatrial entrance block prevents reentry during spontaneous SA node discharge.
    • AV nodal reentry can initiate tachycardia via alternative pathways.
    • Unidirectional block in working atrial myocardium facilitates circus movement tachycardia, supporting the "leading circle" model.

    Conclusions:

    • Premature beats are potent triggers for reentrant arrhythmias in the atria.
    • The "leading circle" concept provides a model for understanding circus movement tachycardia, even without anatomical obstacles.
    • These findings have implications for understanding and potentially treating supraventricular tachycardias.