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Updated: Aug 11, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
Published on: March 3, 2021
[Mechanisms of development of thermoregulatory tone and cold shivering]
Abstract:
In rabbits, muscle potentials in response to factors increasing (low external temperature, inhalation of helium - oxygen mixture, electrical stimulation of the posterior hypothalamus) and decreasing the thermoregulatory muscle activity (high external temperature, inhalation of hypoxic mixture, electrical stimulation of the anterior preoptic hypothalamus), were studied. The thermoregulatory muscle tone and the cold chiver were shown to be independent forms of specific muscle activity with different regulating mechanisms. The increase or decrease of the muscles electrical activity occur because of a change of the muscle potentials amplitude rather than a change of the muscle oscillations frequency.
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