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[Growth hormone in the newborn infant during the first 6 days of life]
Fortschritte Der Medizin
|October 9, 1975
Insights
Newborns have high Human Growth Hormone (HGH) levels, which drop around day 3-4 as they regain birth weight. Infant HGH levels are independent of maternal HGH.
Area of Science:
- Endocrinology
- Neonatal Physiology
Context:
- Human Growth Hormone (HGH) plays a crucial role in infant development.
- Understanding neonatal HGH dynamics is essential for assessing infant health and growth patterns.
Purpose:
- To investigate the typical concentration and pattern of Human Growth Hormone (HGH) in newborns during the first few days of life.
- To determine the relationship between HGH levels, weight changes, and maternal HGH influence.
Summary:
- Newborn serum Human Growth Hormone (HGH) concentrations are approximately 61 ng/ml initially, decreasing significantly between the third and fourth postnatal days.
- This decline in HGH correlates with the transition from neonatal weight loss to weight gain.
- Evidence suggests that neonatal HGH is not maternally derived.
Impact:
- Provides baseline data for neonatal HGH levels, aiding in the identification of potential growth disorders.
- Clarifies the endogenous nature of neonatal HGH, distinguishing it from maternal sources.
- Contributes to a better understanding of infant metabolic adjustments and growth regulation post-birth.
Abstract:
Human Growth Hormone (HGH) of the newborn during its first days of life is approximately 61 ng/ml, then it falls between the third and fourth day. This fall in serum concentration principally occurs when the infant stops losing weight and starts regaining it. Experiences show that HGH of newborn does not stem from the mother.