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[Is factor XII deficiency a contraindication to surgery?].

B Neidhardt, U P Eckhoff, K T Schricker

    Fortschritte Der Medizin
    |October 16, 1975
    PubMed
    Summary

    This study details a successful pelvic surgery on a patient with Hageman factor deficiency (Factor XII). The patient experienced no complications, demonstrating safe surgical management for Factor XII deficiency.

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    Area of Science:

    • Hematology
    • Surgical Oncology
    • Orthopedic Surgery

    Background:

    • Hageman factor deficiency (Factor XII deficiency) is a rare bleeding disorder.
    • Surgical procedures in patients with Factor XII deficiency require careful management due to potential bleeding risks.

    Observation:

    • A case report of an 18-year-old female with moderately severe Hageman factor deficiency (Factor XII at 2.5%) is presented.
    • The patient underwent a Chiari osteotomy of the pelvis.

    Findings:

    • The surgical procedure and postoperative recovery were uneventful.
    • No abnormal bleeding tendencies or complications were observed.
    • Blood transfusions were not required.

    Implications:

    • This case suggests that major orthopedic surgery can be safely performed in patients with Hageman factor deficiency.
    • Establishes guidelines for surgical procedures in individuals with Factor XII deficiency.
    • Highlights the importance of individualized patient management in rare bleeding disorders.

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