Related Experiment Video
Updated: Aug 18, 2026
07:41
Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
Published on: October 23, 2020
A correlative study on the occurrence of retinopathy and nephropathy in sucrose-fed diabetic rats
Acta Diabetologica Latina
|January 1, 1975
Abstract:
The correlation of the occurrence of renal and retinal microangiopathy was studied in 139 genetically selected sucrose-fed diabetic rats. It was found that in 13% of the animals both retinal and renal lesions developed; in 20% only diabetic retinopathy and in 10% diffuse glomerulosclerosis alone was observed.
Related Concept Videos
01:27Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
01:28Diabetic Nephropathy
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...