Immunological studies with aortic and venous tissue antigens. I. The antigen structure of vascular tissues

Fractionation of intact and arteriosclerotic aortic and venous intimas was performed. The distribution of the obtained fractions (CTC, CSC, collagen, SGP and elastin), their disc-electrophoretic and immunological behaviour was studied. With the process of arteriosclerosis a decrease of the structural proteins (collagen, SGP, elastin) and an increase in the amount of some proteins of plasmatic origin could be demonstrated. By the use of absorbed immune sera in the immunoelectrophoretic patterns of aortic and venous CTC-extracts two vessel wall specific arcs were found.