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[Typhoid encefalopathy followed by permanent memory defects (author's transl)]
Rivista Di Patologia Nervosa E Mentale
|September 1, 1975
Summary
Typhoid fever can cause acute encephalopathy in adolescents, leading to severe neurological deficits like memory loss. Early diagnosis and treatment are crucial to prevent long-term cognitive impairment.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Typhoid fever, a systemic infection caused by Salmonella Typhi, can present with diverse neurological complications.
- Acute encephalopathy is a rare but serious manifestation of typhoid fever.
Observation:
- An 18-year-old female presented with sudden coma, followed by stupor, complex hyperkinesias, and aphonia lasting 15-20 days.
- The clinical presentation was indicative of acute encephalopathy.
Findings:
- The encephalopathy was diagnosed as being caused by typhoid fever.
- Neurological follow-up revealed severe permanent memory impairment and some degree of mental deterioration.
- Basal ganglia signs resolved over time.
Implications:
- This case highlights the potential for severe neurological sequelae following typhoid fever, even in young adults.
- It underscores the importance of considering infectious etiologies, such as typhoid fever, in cases of acute encephalopathy with movement disorders.
- Long-term cognitive deficits necessitate comprehensive rehabilitation and support for affected individuals.