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Characterizing electroosmotic flow in microfluidic devices.

J Gaudioso1, H G Craighead

  • 1Department of Applied Physics and Engineering, Cornell University, Ithaca, NY 14853, USA.

Journal of Chromatography. A
|September 28, 2002
PubMed
Summary
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Electroosmotic flow (EOF) in microfluidic devices was measured. Oxidized zeonor plastic showed similar EOF responses to glass, but its surface degrades. Surfactant coatings suppressed EOF, requiring days to stabilize.

Area of Science:

  • Microfluidics
  • Surface Chemistry

Background:

  • Electroosmotic flow (EOF) is crucial for fluid manipulation in microfluidic devices.
  • Borosilicate glass is a common material, but alternatives like zeonor plastic are desirable for cost and fabrication.
  • Understanding EOF behavior in different materials and surface treatments is essential for device optimization.

Purpose of the Study:

  • To measure and compare electroosmotic flow (EOF) in borosilicate glass capillaries and zeonor plastic microfluidic devices.
  • To investigate the stability and performance of oxidized zeonor surfaces for supporting EOF.
  • To evaluate the impact of common surfactant coatings on EOF in these devices.

Main Methods:

  • Utilized a current-monitoring method to quantify EOF.
  • Employed surface oxidation treatment for zeonor plastic microfluidic devices.

Related Experiment Videos

  • Tested responses to variations in applied electric field, pH, and ionic concentration.
  • Applied and analyzed the effects of dynamic surfactant coatings (POP-6, POP4, Pluronics L81, NP-40).

    • Main Results:

    • Oxidized zeonor plastic surfaces supported EOF and exhibited similar responses to applied field, pH, and ionic concentration as borosilicate glass.
    • The surface oxidation treatment on zeonor showed signs of aging and degradation within 6 days.
    • Dynamic surfactant coatings generally suppressed EOF, with stabilization occurring over several days.

    Conclusions:

    • Zeonor plastic, when oxidized, can serve as a viable alternative to glass for microfluidic applications requiring EOF.
    • The stability of oxidized zeonor surfaces is a critical factor limiting long-term device performance.
    • Surfactant coatings offer a method to control EOF, but their long-term effects and stabilization times need consideration.