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Bioactive constituents of Cedrelopsis microfoliata
Neil A Koorbanally1, Milijaona Randrianarivelojosia, Dulcie A Mulholland
1Natural Products Research Group, Department of Chemistry, University of Natal, Durban, 4041, South Africa.
Journal of Natural Products
|September 28, 2002
Abstract:
The stem bark of Cedrelopsis microfoliata has yielded the new compounds microfolian (1), microfolione (2), and microfolicoumarin (6) along with the known compounds agrandol (3), cedrecoumarin A (4), obliquin (5), and sesquichamaenol (7). Compounds 2-4 were found to show agonistic activity on both alpha- and beta-estrogenic receptors, and compounds 1, 3, and 4 were shown to inhibit the chemiluminescence of reactive oxygen metabolites and showed superoxide scavenging activity.