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Differentiation of prostate cancer from benign prostate hypertrophy using dual-echo dynamic contrast MR imaging
Satoshi Muramoto1, Hidemasa Uematsu, Hirohiko Kimura
1Department of Radiology, Fukui Medical University, 23 Shimoaizuki, Matsuoka, Yoshida, Fukui 910-1193, Japan. muramoto@fmsrsa.fukui-med.ac.jp
Objective:
To investigate the usefulness of dynamic contrast magnetic resonance (MR) imaging in the differentiation of prostate cancer (PC) from benign prostate hypertrophy (BPH).
Materials And Methods:
Eleven PC patients and 13 BPH patients were entered into the analysis. The mean gradient (MG) was calculated from the T2* term-eliminated time-signal intensity curve obtained from dynamic contrast MR data, and the MG of PC and that of BPH were compared.
Results:
The MG of PC was significantly higher than that of BPH. When the threshold value was set to 1.88% per s for discriminating PC from BPH, the sensitivity, specificity, and accuracy were 100, 85, and 92%, respectively.
Conclusion:
The MG, which is derived from the T2* term-eliminated time-signal intensity curve, may be a useful index for differentiating PC from BPH.