[Myocardial damage syndrome in allergic conditions]

Experimental and clinical studies were conducted that permitted to suggest a possible direct damaging effect of allergy upon the myocardium. Distinct types of allergic reactions of the myocardium were singled out in cases of the states being studied, namely infectious-allergic myocarditis and bronchial asthma. The reactions observed in infectious-allergic myocarditis pertain to hypersensitivity of a delayed type which morphological manifestation is embodied in cellular lymphohistocytic, monocytic perivascular infiltration and myocardial stroma damage. In bronchial asthma haemodynamic disorders are noted in the vessels of the microcirculatory bed, as well as oedema of the stroma and muscle fibers destruction.