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Colorectal cancer in Egypt.

Ahmed A Abou-Zeid1, Wael Khafagy, Deya M Marzouk

  • 1Unit 6, Department of Surgery, El Demerdash Hospital, Ain Shams University, Cairo, Egypt.

Diseases of the Colon and Rectum
|September 28, 2002
PubMed
Summary

Colorectal cancer in Egypt affects a young population, with over a third of cases occurring in individuals under 40. The disease often presents at advanced stages and is not linked to hereditary factors or bilharziasis.

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Area of Science:

  • Oncology
  • Gastroenterology
  • Epidemiology

Background:

  • Colorectal cancer (CRC) presents unique epidemiological patterns globally.
  • Understanding age distribution and pathological features is crucial for effective public health strategies.

Purpose of the Study:

  • To investigate the age distribution and pathology of colorectal adenocarcinoma in Egypt.
  • To compare findings across different major hospitals in Egypt.

Main Methods:

  • A seven-year review of 177 colorectal adenocarcinoma patients (19-74 years) at Ain Shams University.
  • Data collection included retrospective analysis of patient files and prospective family history assessment.
  • Comparison with data from three other major Egyptian hospitals.

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Main Results:

  • CRC in Egypt shows no specific age predilection, with 38% of tumors in patients under 40.
  • The majority of tumors (75%) were located on the left side, with 58% at Dukes C stage.
  • Predisposing adenomas were rare (5.6%), and bilharziasis was found in 3.4% of specimens.

Conclusions:

  • Egyptian colorectal cancer predominantly affects a young demographic, unexplained by hereditary factors or bilharziasis.
  • The disease frequently presents at advanced stages with infrequent adenomas.
  • Consistent data across centers suggest a distinct epidemiological profile for CRC in Egypt.