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The potential role of probiotics in pediatric urology
1Canadian Research and Development Centre for Probiotics, Lawson Health Research Institute and Department of Microbiology, University of Western Ontario, London, Canada.
Insights
Probiotic therapy, using live beneficial bacteria, shows promise in pediatric urology. It may help reduce infections and stone disease, and potentially manage inflammatory and carcinogenic conditions.
Area of Science:
- Microbiology
- Pediatric Urology
- Gastroenterology
Background:
- The role of microflora in pediatric health and disease is increasingly recognized.
- Urinary tract infections (UTIs) are common in children and can recur into adulthood.
- Intestinal and urogenital microflora significantly impact overall health.
Purpose of the Study:
- To evaluate the potential benefits of probiotic therapy in pediatric urology.
- To explore the link between microflora and urological health in children.
- To review existing literature on probiotics and their application in pediatric urology.
Main Methods:
- Literature review of existing data on probiotics and microflora.
- Examination of the relationship between intestinal and urogenital microflora and urological conditions.
- Presentation of a viewpoint on the relevance of these findings to pediatric urology.
Main Results:
- Evidence suggests specific lactobacilli and bifidobacteria strains are crucial for maintaining health.
- These beneficial bacteria play a key role in restoring health in both children and adults.
- Probiotics demonstrate potential in managing the gut and urogenital microbiome.
Conclusions:
- Probiotic therapy may decrease infection and stone disease risk in pediatric urology.
- Potential benefits include managing inflammatory conditions and possibly preventing certain cancers.
- Modulating the microbiome through probiotics offers a novel therapeutic approach in pediatric urology.
Purpose:
The application of select microbial strains to increase the host population of good bacteria is called probiotics, a term defined as "live microorganisms which when administered in adequate amounts confer a health benefit on the host." This review was done to evaluate the potential role that probiotic therapy may have in pediatric urology.
Materials And Methods:
Many children around the world die of diseases, such as gastrointestinal infection and HIV, while many have urinary tract infections that subsequently recur frequently in adulthood. Until recently the role of intestinal and urogenital (vaginal, urethral and perineal) microflora in health and disease has received scant attention. The data available in the literature on this topic were examined and a personal viewpoint is presented on how they may relate to urology.
Results:
There is mounting evidence that certain strains of lactobacilli and bifidobacteria have a major part in the maintenance and restoration of health in children and adults.
Conclusions:
Implications for pediatric urology include a decreased risk of infection and stone disease as well as possible positive effects on preventing and managing inflammatory and some carcinogenic diseases.
Related Concept Videos
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Probiotics
Introduction to the Human Microbiota
Microbiota of the Urogenital Tract
Microbiota Modulation by Antibiotics

