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Updated: Jul 25, 2026

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
Published on: December 8, 2017
Neuroprotection: the role of neuroglia
1Katedra Biologii Collegium Medicum UJ ul. Kopernika 7, 31-034 Kraków. dziobek@mp.pl
Abstract:
Astrocytes protect neurons against: 1. Glutamate excitotoxicity through exchange of glutamine for glutamate. 2. Reactive oxygen and nitrogen (peroxynitrite) species. 3. Toxins of endo- and exogenous origin e.g. cyanide. Astrocytes and microglia also protect neurons by storing excess iron and by brushing away from the brain tissue damaged cell constituents such as aged mitochondria, peroxidized cytomembranes and nitrated proteins.
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