Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Compositional patterns in reptilian genomes.

Sandrine Hughes1, Oliver Clay, Giorgio Bernardi

  • 1Laboratorio di Evoluzione Molecolare, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121, Naples, Italy.

Gene
|October 2, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatiotemporal control of myoblast identity drives muscle diversity in the <i>Drosophila</i> leg.

Science advances·2026
Same author

Integrative and conjugative elements carrying high-level gentamicin resistance genes in <i>Streptococcus dysgalactiae</i> subsp. <i>equisimilis</i> from horses.

Microbial genomics·2026
Same author

Single-cell transcriptomic profiling of zebrafish primary motor neurons reveals subtype-specific gene expression signatures.

iScience·2025
Same author

SpeckSeq enables high-throughput functional stratification of MEFV variants in autoinflammatory diseases.

The Journal of experimental medicine·2025
Same author

<i>Candida albicans</i> releases a peptide from the Rbt1 protein to promote its invasion into the gut epithelium.

Gut microbes·2025
Same author

Dual-transcriptomics on microdissected cells reveals functional specialisation of symbiont-bearing-cells and contrasted responses to nutritional stress in the cereal weevil.

Microbiome·2025
Same journal

Mutation T71R enhanced the structural stability and functional activity of wild type superoxide dismutase cloned from soil metagenome.

Gene·2026
Same journal

Reduced ATXN1 expression as an adverse prognostic indicator in Acute myeloid leukemia.

Gene·2026
Same journal

Constructing regulatory networks of Rubisco post-translational modifications: a novel avenue for engineering environment adaptive plants.

Gene·2026
Same journal

Traumatic brain injury enhances fracture healing by upregulating VNN1 to activate the Wnt/β-catenin signaling pathway.

Gene·2026
Same journal

Single-cell transcriptomics reveals CCL2-mediated macrophage-endothelial cell interactions drive apoptosis in varicose veins.

Gene·2026
Same journal

Development of a gene signature related to phospholipid metabolism for prognosis and therapeutic Prediction in Osteosarcoma: Focus on VAC14.

Gene·2026
See all related articles

This study analyzed DNA composition in 31 reptilian genomes, particularly snakes, using analytical ultracentrifugation. Results reveal distinct DNA density patterns separating snakes from other reptiles, offering new insights into sauropsid genome evolution.

Area of Science:

  • Genomics
  • Molecular Biology
  • Evolutionary Biology

Background:

  • Sauropsids, including reptiles and birds, represent a diverse vertebrate group.
  • While avian genomes are well-studied, reptilian genomes remain largely uncharacterized.
  • Limited nuclear sequence data is available for non-avian sauropsids.

Purpose of the Study:

  • To analyze DNA compositional patterns (GC distributions) in 31 reptilian genomes.
  • To characterize these patterns using parameters like modal buoyant density, mean buoyant density, asymmetry, and heterogeneity.
  • To compare compositional properties across different reptilian groups and with other vertebrate classes.

Main Methods:

  • Analytical ultracentrifugation of DNA in Cesium Chloride (CsCl) gradients.

Related Experiment Videos

  • Analysis of DNA compositional patterns, including modal buoyant density, mean buoyant density, asymmetry, and heterogeneity.
  • Comparative analysis of 31 reptilian genomes, with a focus on snakes.

    • Main Results:

    • Reptilian DNA buoyant densities clearly distinguished two groups: snakes and other reptiles (crocodiles, turtles, lizards).
    • Snakes exhibited modal densities similar to mammals, while crocodiles, turtles, and lizards showed higher densities.
    • Snake genomes displayed broad ranges of asymmetry and heterogeneity, whereas crocodiles and turtles showed narrower, intermediate ranges.

    Conclusions:

    • DNA compositional analysis provides a clear distinction between snake and other reptilian genomes.
    • The findings suggest unique evolutionary trajectories for snake genomes compared to other sauropsids.
    • This study contributes valuable genomic data for understanding reptilian diversity and evolution.